Team.
János Fuzik.
János Fuzik is an interdisciplinary neuroscientist and Assistant Professor of neuroscience at the Dept. of Neuroscience at Karolinska Institute in Stockholm, Sweden. His research seeks to understand the neuronal circuit correlates of anxiety disorders from complete circuits down to the specific connections between specific neuronal types. The Fuzik Lab’s experimental approach combines all-optical voltage imaging, mouse behavior, and molecular biology to uncover the synaptic mechanisms that underly the maladaptive re-routing of threatful information resulting in anxiety.
Current members.
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Veronika Csillag
Postdoctoral Researcher
Veronika Csillag is a postdoctoral researcher in the Fuzik Lab. Veronika's main background is hormonal neuromodulation and electrophysiology in the brain. She is interested to understand the neuronal connectivity changes underlying the development of brain states in mouse models of anxiety. She is using all-optical voltage imaging in combination with anatomical and molecular approaches to address her questions about neuronal circuit maladaptation in anxiety.
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Gréta Martina Szücs
PhD Student
Gréta Martina Szücs is a PhD student in the Fuzik Lab. Gréta seeks to understand the disinhibitory circuits of deep brain structures that regulate defensive behaviors. She investigates the molecular identity and synaptic connectivity of inhibitory neurons using single-cell RNA-sequencing, anatomical tracing, all-optical voltage imaging and electrophysiology. Her goal is to understand how inhibition of inhibition - a fine regulation of neuronal circuits - gates and controls defensive behaviors and gets impaired in brain states of anxiety.
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Inés Talaya Vidal
Lab Assistant
Inés Talaya Vidal is a Lab Assistant in the Fuzik Lab. Inés aimes to understand how threatful information induces defensive behaviors. Inés uses a psychological stressor, predator scent, to induce long-lasting circuit maladaptation as a model of PTSD and uses machine learning-based and custom-written analysis to obtain a detailed understanding of the resulting behavioral changes. She is interested to untangle the neuronal mechanisms underlying susceptibility to stress.
Alumni.
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Marianne Bizzozzero Hiriart
Marianne Bizzozzero Hiriart was a postdoctoral researcher in the Fuzik Lab. Her main background is GABAergic regulation in the hypothalamus. She is interested in understanding the defensive behaviors driven by hypothalamic pathways and uses viral pathway labeling and in vivo optogenetic activation of the labeled pathways during behavior in awake mice.
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Gabriela Da Cruz Meda
Gabriela Da Cruz Meda was a master student in the Fuzik Lab. She worked on understanding the anatomy of collateral hypothalamic projections that innervate the brain stem and brain pathways the drive defensive behavior such as the anterior hypothalamus.
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Samuel Edgar
Samuel Edgar was a master student in the Fuzik Lab. He worked on the spatial mapping of lateral hypothalamic neurons that innervate the lateral habenula and medial hypothalamic neurons that project to the periaqueductal gray matter.